Nicotine therapeutic benefits: Difference between revisions

Line 492:

**Citation: Zhang W, Lin H, Zou M, Yuan Q, Huang Z, Pan X and Zhang W (2022) Nicotine in Inflammatory Diseases: Anti-Inflammatory and Pro-Inflammatory Effects. Front. Immunol. 13:826889. doi: 10.3389/fimmu.2022.826889

***Acknowledgements: This work was supported by the National Natural Science Foundation of China (grant number 81903319), Natural Science Foundation of Guangdong Province of China (grant number 2021A1515011220), Administration of Traditional Chinese Medicine of Guangdong Province of China (grant number 20211008), Special Fund for Young Core Scientists of Agriculture Science (grant number R2019YJ-QG001), Special Fund for Scientific Innovation Strategy—Construction of High-Level Academy of Agriculture Science (grant number R2018YJ-YB3002), Top Young Talents of Guangdong Hundreds of Millions of Projects of China (grant number 87316004), the foundation of director of Crops Research Institute, Guangdong Academy of Agricultural Sciences (grant number 202205) and Outstanding Young Scholar of Double Hundred Talents of Jinan University of China.

===2020 [https://www.sciencedirect.com/science/article/abs/pii/S000927971931734X Nicotine-induced autophagy via AMPK/mTOR pathway exerts protective effect in colitis mouse model]===

*Animal study

*Conclusion: "Taken together, we demonstrated that nicotine inhibits apoptosis

and proliferation by modulating AMPK/mTOR pathway-mediated autophagy and improves colitis severity in the DSS-induced UC mouse

model. These findings provide new insights into the mechanism of nicotine treatment on UC-autophagy. Further exploration of the mechanism of nicotine in autophagy and targeting factors might be considered a new approach for ulcerative colitis treatment."

*[https://sci-hub.st/10.1016/j.cbi.2020.108943 PDF Full paper]

**Citation: Gao Q, Bi P, Luo D, Guan Y, Zeng W, Xiang H, Mi Q, Yang G, Li X, Yang B. Nicotine-induced autophagy via AMPK/mTOR pathway exerts protective effect in colitis mouse model. Chem Biol Interact. 2020 Feb 1;317:108943. doi: 10.1016/j.cbi.2020.108943. Epub 2020 Jan 10. PMID: 31926917.

***Acknowledgement: This work was supported by the Yunnan Key Laboratory of Tobacco Chemistry Project [Grant No. 2017539200340397].

===2018 [https://academic.oup.com/jleukbio/article-abstract/104/5/1013/6935503 Nicotine treatment ameliorates DSS-induced colitis by suppressing MAdCAM-1 expression and leukocyte recruitment]===

@@ Line 492: / Line 492: @@
 **Citation: Zhang W, Lin H, Zou M, Yuan Q, Huang Z, Pan X and Zhang W (2022) Nicotine in Inflammatory Diseases: Anti-Inflammatory and Pro-Inflammatory Effects. Front. Immunol. 13:826889. doi: 10.3389/fimmu.2022.826889
 ***Acknowledgements: This work was supported by the National Natural Science Foundation of China (grant number 81903319), Natural Science Foundation of Guangdong Province of China (grant number 2021A1515011220), Administration of Traditional Chinese Medicine of Guangdong Province of China (grant number 20211008), Special Fund for Young Core Scientists of Agriculture Science (grant number R2019YJ-QG001), Special Fund for Scientific Innovation Strategy—Construction of High-Level Academy of Agriculture Science (grant number R2018YJ-YB3002), Top Young Talents of Guangdong Hundreds of Millions of Projects of China (grant number 87316004), the foundation of director of Crops Research Institute, Guangdong Academy of Agricultural Sciences (grant number 202205) and Outstanding Young Scholar of Double Hundred Talents of Jinan University of China.
+===2020 [https://www.sciencedirect.com/science/article/abs/pii/S000927971931734X Nicotine-induced autophagy via AMPK/mTOR pathway exerts protective effect in colitis mouse model]===
+*Animal study
+*Conclusion: "Taken together, we demonstrated that nicotine inhibits apoptosis
+and proliferation by modulating AMPK/mTOR pathway-mediated autophagy and improves colitis severity in the DSS-induced UC mouse
+model. These findings provide new insights into the mechanism of nicotine treatment on UC-autophagy. Further exploration of the mechanism of nicotine in autophagy and targeting factors might be considered a new approach for ulcerative colitis treatment."
+*[https://sci-hub.st/10.1016/j.cbi.2020.108943 PDF Full paper]
+**Citation: Gao Q, Bi P, Luo D, Guan Y, Zeng W, Xiang H, Mi Q, Yang G, Li X, Yang B. Nicotine-induced autophagy via AMPK/mTOR pathway exerts protective effect in colitis mouse model. Chem Biol Interact. 2020 Feb 1;317:108943. doi: 10.1016/j.cbi.2020.108943. Epub 2020 Jan 10. PMID: 31926917.
+***Acknowledgement: This work was supported by the Yunnan Key Laboratory of Tobacco Chemistry Project [Grant No. 2017539200340397].
 ===2018 [https://academic.oup.com/jleukbio/article-abstract/104/5/1013/6935503 Nicotine treatment ameliorates DSS-induced colitis by suppressing MAdCAM-1 expression and leukocyte recruitment]===